Bilcare Research Website Konzept und Kalkulation - PAGE-AND-PAPER_


LiveoOptima™ is the first scientific method to determine the most cost effective blister packaging for solid dosage pharmaceutical products, following FDA recommended QbD principle. This patented technology determines the right barrier required to protect the product and maintain its efficacy. LiveoOptimaTM’s enhanced formulation analysis leads to the most cost effective barrier films to the requested shelf life period in all desired climatic conditions.

Discover how your product formulation can be scientifically matched to the optimal package with Liveo Research‘s scientific packaging services.


Science for better packaging 

This process deduces the optimum packaging through a comprehensive drug sensitivity profiling, the output is not only a scientific background on packaging selection, but also a deep understanding of the product’s strengths and weaknesses. This sought after Liveo Research service has proven to provide up to 50% packaging cost reduction without compromising its quality and provided invaluable product knowledge to make faster, scientifically correct commercially beneficial decisions.

Traditional “trial and error” approach which wastes scientific time and resources will be replaced by commercial beneficial “right first time” solution while satisfying all regulatory and technical needs.

The LiveoOptima™ Methodology

  • Degradation pattern of formulation is evaluated using a set of designed experiments
  • Three batches are studied under various environmental conditions
  • Effects of environmental variables on product critical stability attributes is assessed
  • Estimates critical factors that determine failure mode and its threshold values
  • Product sensitivity is quantified against each environmental factor
  • Design the ideal blister cavity based on specific dose size and shape
  • Simulate Cavity Thinning & Moisture Permeation through FEA Software to predict real-life MVTR
  • Select the optimum blister film and foil lidding combination to get best shelf life
Time to market makes the difference
Liveo Research’s scientifically streamlined  FastPack®  process identifies optimal packaging prior to stability study and can be utilized when time to market is critical or determine package to overcome stability failures in 15 business days.
From Liveo Research’s two decades long research on various commercially available solid dosage formulations and information derived from hundreds of LiveoOptimaTM projects, Liveo Research Scientists were able to learn step by step from this experience. This leads to the development of a simpler and faster determination of the ideal packaging choice for stability study. Liveo Research‘s fast packaging determination is built upon data and definitive correlations between changes in certain physical characteristics attributable to moisture and/or light induced stability failures in solid dosage form. Like in the case of LiveoOptimaTM the selection is done based on the product sensitivity study towards the environmental variables, but without requiring any chemical analytical support. This may not be as comprehensively applicable as LiveoOptimaTM, but is currently the most used tool to determine the right package for solid dosage formulation.

The Liveo +

Quality and Regulatory

Product inquiry​

Scroll to Top