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LiveoOptima™

Name: LiveoOptimaTM - Liveo Research GmbH
Availability: InStock

LiveoOptima™ is the first scientific method to determine the most cost effective blister packaging for solid dosage pharmaceutical products, following FDA recommended QbD principle. This patented technology determines the right barrier required to protect the product and maintain its efficacy. LiveoOptima^TM’s enhanced formulation analysis leads to the most cost effective barrier films to the requested shelf life period in all desired climatic conditions.

Discover how your product formulation can be scientifically matched to the optimal package with Liveo Research‘s scientific packaging services.

LiveoOptima^TM

FastPack^®

LiveoOptima^TM

FastPack^®

LiveoOptima™

Science for better packaging

This process deduces the optimum packaging through a comprehensive drug sensitivity profiling, the output is not only a scientific background on packaging selection, but also a deep understanding of the product’s strengths and weaknesses. This sought after Liveo Research service has proven to provide up to 50% packaging cost reduction without compromising its quality and provided invaluable product knowledge to make faster, scientifically correct commercially beneficial decisions.

Traditional “trial and error” approach which wastes scientific time and resources will be replaced by commercial beneficial “right first time” solution while satisfying all regulatory and technical needs.

The LiveoOptima™ Methodology

Degradation pattern of formulation is evaluated using a set of designed experiments
Three batches are studied under various environmental conditions
Effects of environmental variables on product critical stability attributes is assessed
Estimates critical factors that determine failure mode and its threshold values
Product sensitivity is quantified against each environmental factor
Design the ideal blister cavity based on specific dose size and shape
Simulate Cavity Thinning & Moisture Permeation through FEA Software to predict real-life MVTR
Select the optimum blister film and foil lidding combination to get best shelf life

FastPack^®

Time to market makes the difference

Liveo Research’s scientifically streamlined FastPack^® process identifies optimal packaging prior to stability study and can be utilized when time to market is critical or determine package to overcome stability failures in 15 business days.

From Liveo Research’s two decades long research on various commercially available solid dosage formulations and information derived from hundreds of LiveoOptima^TM projects, Liveo Research Scientists were able to learn step by step from this experience. This leads to the development of a simpler and faster determination of the ideal packaging choice for stability study. Liveo Research‘s fast packaging determination is built upon data and definitive correlations between changes in certain physical characteristics attributable to moisture and/or light induced stability failures in solid dosage form. Like in the case of LiveoOptimaTM the selection is done based on the product sensitivity study towards the environmental variables, but without requiring any chemical analytical support. This may not be as comprehensively applicable as LiveoOptima^TM, but is currently the most used tool to determine the right package for solid dosage formulation.

The Liveo +

Outstanding customer service representatives
Global and on-site application engineering support
Local languages spoken by knowledgeable indigenous sales representatives
Central point of contact for easy communication
Low development costs
Perfect product protection in respective climatic zone
Avoidance of over packaging due to incorrect foil specification
Reduction of waste, overpackaging and costs
New film formulations developed in conjunction with customer input and requirements